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Aurélie Labbe

Associate Professor,  Department of Decision Sciences

Aurélie Labbe

Contact information

HEC Montréal
3000, chemin de la Côte-Sainte-Catherine
Montréal (Québec)
Canada H3T 2A7

Email: aurelie.labbe@hec.ca
Phone: 514 340-3181
Secretary: 514 340-6472
Fax: 514 340-5634
Office: 4.821

Other title(s)

Member of Centre de recherches mathématiques


  • Doctorat (statistique), University of Waterloo
  • Maîtrise (statistique), Université de Montréal
  • Licence (mathématiques appliquées et sciences sociales), Université Paris-Dauphine
  • Licence (mathématiques pures), Université Versailles-St Quentin

This publication selection covers the last five years.


Journal articles (38)

PASCOAL, Tharick A., MATHOTAARACHCHI, Sulantha, SHIN, Monica, LESSA BENEDET, Andréa, MOHADES, Sara, WANG, Seqian, BEAUDRY, Thomas, KANG, Min Su, SOUCY, Jean-Paul, LABBE, Aurélie, GAUTHIER, Serge, ROSA NETO, Pedro; « Synergistic interaction between amyloid and tau predicts the progression to dementia », Alzheimer's and Dementia: The Journal of the Alzheimer's Association, vol. 13, no 6, 2017, p. 644-653.

FOREST, Marie, ITURRIA-MEDINA, Yasser, GOLDMAN, Jennifer, KLEINMAN, Claudia L., LOVATO, Amanda, KLEIN OROS, Kathleen, EVANS, Alan, CIAMPI, Antonio, LABBE, Aurélie, M.T. GREENWOOD, Celia; « Gene networks show associations with seed region connectivity », Human Brain Mapping, vol. 38, no 6, 2017, p. 3126-3140.

MATHOTAARACHCHI, Sulantha, WANG, Seqian, SHIN, Monica, PASCOAL, Tharick A., LESSA BENEDET, Andréa, KANG, Min Su, BEAUDRY, Thomas, FONOV, Vladimir S., GAUTHIER, Serge, LABBE, Aurélie, ROSA NETO, Pedro; « VoxelStats: A MATLAB Package for Multi-Modal Voxel-Wise Brain Image Analysis », Frontiers in Neuroinformatics, vol. 10, no 20, 2016.

O. HUANG, Lam, INFANTE-RIVARD, Claire, LABBE, Aurélie; « Analysis of Case-Parent Trios Using a Loglinear Model with Adjustment for Transmission Ratio Distortion », Frontiers in Genetics, vol. 7, 2016, p. 155-165.

BHATNAGAR, Sahir, M.T. GREENWOOD, Celia, LABBE, Aurélie; « Assessing transmission ratio distortion in extended families: a comparison of analysis methods », BMC Proceedings, vol. 10(Suppl 7), no 12, 2016, p. 197-202.

STEIGER, Howard, THALER, Lea, GAUVIN, Lise, JOOBER, Ridha, LABBE, Aurélie, ISRAEL, Mimi, KUCER, Audrey; « Epistatic interactions involving DRD2, DRD4, and COMT polymorphisms and risk of substance abuse in women with binge-purge eating disturbances », Journal of Psychiatric Research, vol. 77, 2016, p. 8-14.

KLEIN OROS, Kathleen, GRINEK, Stepan, BERNATSKY, Sasha, BOUCHARD, Luigi, CIAMPI, Antonio, COLMEGNA, Ines, FORTIN, Jean-Philippe, GAO, long, HIVERT, Marie-France, HUDSON, Marie, KOBOR, Michael Steffen, LABBE, Aurélie, MACISAAC, Julie, MEANEY, Michael, MORIN, Alexander, O'DONNELL, Kieran, PASTINEN, Tomi, VAN IJZENDOORN, Marinus, VOISIN, Grégory, M.T. GREENWOOD, Celia; « funtooNorm: an R package for normalization of DNA methylation data when there are multiple cell or tissue types », Bioinformatics, vol. 32, no 4, 2016, p. 593-595.

PASCOAL, Tharick A., MATHOTAARACHCHI, Sulantha, MOHADES, Sara, LESSA BENEDET, Andréa, CHUNG, Chang Oh, SHIN, Monica, WANG, Seqian, BEAUDRY, Thomas, KANG, Min Su, SOUCY, Jean-Paul, LABBE, Aurélie, GAUTHIER, Serge, ROSA NETO, Pedro; « Amyloid-β and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer's disease », Molecular Psychiatry, vol. 22, no 2, 2016, p. 306-311.

VILLANDRE, Luc, STEPHENS, David A., LABBE, Aurélie, GÜNTHARD, Huldrych, KOUYOS, Roger, STADLER, Tanja; « Assessment of Overlap of Phylogenetic Transmission Clusters and Communities in Simple Sexual Contact Networks: Applications to HIV-1 », PLOS ONE, vol. 11, no 2, 2016.

DUCHARME, Simon, ALBAUGH, Matthew, NGUYEN, Tuong-Vi, HUDZIAK, James J, MATEOS PÉREZ, José María, LABBE, Aurélie, EVANS, Alan, KARAMA, Sherif; « Trajectories of cortical thickness maturation in normal brain development--The importance of quality control procedures », NeuroImage, vol. 125, 2016, p. 267-279.

DUBOIS, Jonathan M., ROUSSET, Olivier, ROWLEY, Jared, PORRAS-BETANCOURT, Manuel, READER, Andrew, LABBE, Aurélie, MASSARWEH, Gassan, SOUCY, Jean-Paul, ROSA NETO, Pedro, KOBAYASHI, Eliane; « Characterization of age/sex and the regional distribution of mGluR5 availability in the healthy human brain measured by high-resolution [(11)C]ABP688 PET », European Journal of Nuclear Medicine and Molecular Imaging, vol. 43, no 1, 2016, p. 152-162.

MCGREGOR, Kevin, BERNATSKY, Sasha, COLMEGNA, Ines, HUDSON, Marie, PASTINEN, Tomi, LABBE, Aurélie, M.T. GREENWOOD, Celia; « An evaluation of methods correcting for cell-type heterogeneity in DNA methylation studies », Genome Biology, vol. 17, no 84, 2016.

TURGEON, Maxime, OUALKACHA, Karim, CIAMPI, Antonio, MIFTAH, Hanane, DEHGHAN, Golsa, ZANKE, Brent W., LESSA BENEDET, Andréa, ROSA NETO, Pedro, M.T. GREENWOOD, Celia, LABBE, Aurélie; « Principal component of explained variance: An efficient and optimal data dimension reduction framework for association studies », Statistical Methods in Medical Research, 2016 (status : accepted).

DUCHARME, Simon, ALBAUGH, Matthew, NGUYEN, Tuong-Vi, HUDZIAK, James J, MATEOS PÉREZ, José María, LABBE, Aurélie, EVANS, Alan, KARAMA, Sherif; « Trajectories of cortical surface area and cortical volume maturation in normal brain development », Data in Brief, vol. 5, 2015, p. 929-938.

LABBE, Aurélie et al.; « Decreased Expression of Nociceptin/Orphanin FQ in the dorsal Anterior Cingulate Cortex of Suicides », European Neuropsychopharmacology, vol. 25, no 11, 2015, p. 2008-2014.

ROMDHANI, Hela, HWANG, Heungsun, PARADIS, Gilles, ROY-GAGNON, Marie-Hélène, LABBE, Aurélie; « Pathway-based association study of multiple candidate genes and multiple traits using structural equation models », Genetic Epidemiology, vol. 39, no 2, 2015, p. 101-113.

LESSA BENEDET, Andréa, LABBE, Aurélie, LEMAY, Philippe, RIGON ZIMMER, Eduardo, PASCOAL, Tharick A., LEUZY, Antoine, MATHOTAARACHCHI, Sulantha, MOHADES, Sara, SHIN, Monica, DIONNE-LAPORTE, Alexandre, BEAUDRY, Thomas, PICARD, Cynthia, GAUTHIER, Serge, POIRIER, Judes, ROULEAU, Guy, ROSA NETO, Pedro; « Epistasis analysis links immune cascades and cerebral amyloidosis », Journal of Neuroinflammation, vol. 15, no 227, 2015.

O’LOUGHLIN, Jennifer, DUGAS, Erika, BRUNET, Jennifer, DIFRANZA, Joseph, ENGERT, James, GERVAIS, André, GRAY-DONALD, Katherine, KARP, Igor, LOW, Nancy, SABISTON, Catherine, SYLVESTRE, Marie-Pierre, TYNDALE, Rachel, AUGER, Nathalie, BÉLANGER, Mathieu, BARNETT, Tracie, CHAITON, Michael, CHENOWETH, Meghan J., CONSTANTIN, Evelyn, CONTRERAS, Gisèle, KAKINAMI, Lisa, LABBE, Aurélie, MAXIMOVA, Katerina, MCMILLAN, Élizabeth, O'LOUGHLIN, Erin K, PABAYO, Roman, ROY-GAGNON, Marie-Hélène, TREMBLAY, Michèle, WELLMAN, Robert J., VAN HULST, Andraea, PARADIS, Gilles; « Cohort Profile: The Nicotine Dependence in Teens (NDIT) Study », International Journal of Epidemiology, vol. 44, no 5, 2014, p. 1537-1546.

FORTIN, Jean-Philippe, LABBE, Aurélie, LEMIRE, Mathieu, ZANKE, Brent W., HUDSON, Thomas J., FERTIG, Elana J., M.T. GREENWOOD, Celia, HANSEN, Kasper D.; « Functional normalization of 450k methylation array data improves replication in large cancer studies », Genome Biology, vol. 15, no 11, 2014, p. 503-.

PEDNEAULT, Maxime, LABBE, Aurélie, ROY-GAGNON, Marie-Hélène, LOW, Nancy, DUGAS, Erika, ENGERT, James, O’LOUGHLIN, Jennifer; « The association between CHRN genetic variants and dizziness at first inhalation of cigarette smoke », Addictive Behaviors, vol. 39, no 1, 2014, p. 316-320.

O’LOUGHLIN, Jennifer, SYLVESTRE, Marie-Pierre, LABBE, Aurélie, LOW, Nancy, ROY-GAGNON, Marie-Hélène, DUGAS, Erika, KARP, Igor, ENGERT, James; « Genetic Variants and Early Cigarette Smoking and Nicotine Dependence Phenotypes in Adolescents », PLOS ONE, vol. 9, no 12, 2014.

IMHOLTE, Gregory, SCOTT-BOYER, Marie-Pier, LABBE, Aurélie, DESCHEPPER, Christian F., GOTTARDO, Raphael; « iBMQ: a R/Bioconductor package for integrated Bayesian modeling of eQTL data. », Bioinformatics, vol. 29, no 21, 2013, p. 2797-2798.

O. HUANG, Lam, LABBE, Aurélie, INFANTE-RIVARD, Claire; « Transmission ratio distortion: review of concept and implications for genetic association studies », Human Genetics, vol. 132, no 3, 2013, p. 245-263.

LOW, Nancy, O’LOUGHLIN, Jennifer, LABBE, Aurélie, ROY-GAGNON, Marie-Hélène, DUGAS, Erika, ENGERT, James; « Genetic determinants vary across early cigarette smoking and nicotine dependence phenotypes in adolescents », Biological Psychiatry, vol. 73, no 9, 2013, p. 289S-.

MALARD, Lucile, KAKINAMI, Lisa, O’LOUGHLIN, Jennifer, ROY-GAGNON, Marie-Hélène, LABBE, Aurélie, PILOTE, Louise, HAMET, Pavel, TREMBLAY, Johanne, PARADIS, Gilles; « The association between the angiotensin-converting enzyme-2 gene and blood pressure in a cohort study of adolescents », BMC Medical Genetics, vol. 14, no 1, 2013, p. 117-.

LABBE, Aurélie; « De la statistique à la génétique, en passant par les mathématiques: identifier les gènes responsables de maladies complexes », Bulletin AMQ - Association mathématique du Québec, vol. LIII, no 2, 2013, p. 55-64.

LABBE, Aurélie, JOOBER, Ridha; « Response to the letter “Actigraphic evaluation for patients with attention deficit/hyperactivity disorder” », American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, vol. 162, no 3, 2013, p. 293-293.

CIAMPI, Antonio, YANG, Lin, LABBE, Aurélie, MÉRETTE, Chantal; « PLS Regression and Hybrid Methods in Genomics Association Studies », Springer Proceedings in Mathematics & Statistics-New Perspectives in Partial Least Squares and Related Methods, vol. 56, 2013, p. 107-116.

GAUTHIER, Serge, JIANPING, Jia, BELLEVILLE, Sylvie, DOUDET, Doris, HSIUNG, Ging-Yuek, LABBE, Aurélie, LI, Dan, QIN, Wei, ROSA NETO, Pedro, SADOVNICK, Dessa, SOUCY, Jean-Paul, WU, Liyong; « Canada-China Cohort Study of early-onset familial Alzheimer's disease », Alzheimer's and Dementia: The Journal of the Alzheimer's Association, vol. 9, no 4, 2013, p. 204-204.

LABBE, Aurélie, DUDOIT, Sandrine; « Special issue on computational statistical methods for genomics and systems biology », Statistical Applications in Genetics and Molecular Biology, vol. 11, no 2, 2012.

OUALKACHA, Karim, LABBE, Aurélie, CIAMPI, Antonio, ROY, Marc-André, MAZIADE, Michel; « Principal components of heritability for high dimension quantitative traits and general pedigrees », Statistical Applications in Genetics and Molecular Biology, vol. 11, no 2, 2012.

LABBE, Aurélie, LIU, Andy, ATHERTON, Juli, GIZENKO, Natalie, SENGUPTA, Sarojini, JOOBER, Ridha; « Refining psychiatric phenotypes for response to treatment: Contribution of LPHN3 in ADHD », American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, vol. 159B, no 7, 2012, p. 776-785.

SCOTT-BOYER, Marie-Pier, IMHOLTE, Gregory, TAYEB, Arafat, LABBE, Aurélie, DESCHEPPER, Christian F., GOTTARDO, Raphael; « An integrated hierarchical Bayesian model for multivariate eQTL mapping », Statistical Applications in Genetics and Molecular Biology, vol. 11, no 4, 2012.

LABBE, Aurélie, BUREAU, Alexandre, MOREAU, Isabel, ROY, Marc-André, CHAGNON, Yvon, MAZIADE, Michel, MÉRETTE, Chantal; « Symptom dimensions as alternative phenotypes to address genetic heterogeneity in schizophrenia and bipolar disorder », European Journal of Human Genetics, vol. 20, no 11, 2012, p. 1182-1188.

GUEVARA, David R., CHAMPIGNY, Marc J., TATTERSALL, Ashley, DEDRICK, Jeff, WONG, Chui E., LI, Yong, LABBE, Aurélie, PING, Chien-Lu, WANG, Yanxiang, NUIN, Paolo, GOLDING, Brian, MCCARRY, Brian, SUMMERS, Peter, MOFFATT, Barbara A., WERETILNYK, Elizabeth A.; « Transcriptomic and metabolomic analysis of Yukon Thellungiella plants grown in cabinets and their natural habitat show phenotypic plasticity », BMC Plant Biology, vol. 12, no 1, 2012, p. 1-17.

MAMDANI, Firoza, BERLIM, Marcelo, BEAULIEU, Marie-Martine, LABBE, Aurélie, MÉRETTE, Chantal, TURECKI, Gustavo; « Gene expression biomarkers of response to citalopram treatment in major depressive disorder », Translational Psychiatry, vol. 1, 2011.

FIORI, Laura M., BUREAU, Alexandre, LABBE, Aurélie, CROTEAU, Jordie, NOËL, Simon, MÉRETTE, Chantal, TURECKI, Gustavo; « Global gene expression profiling of the polyamine system in suicide completers. », The International Journal of Neuropsychopharmacology, vol. 14, no 5, 2011, p. 595-605.


Book chapters (2)

CUNNINGHAM, Erica, CIAMPI, Antonio, JOOBER, Ridha, LABBE, Aurélie; « Estimating and Correcting Optimism Bias in Multivariate PLS Regression: Application to the Study of the Association Between Single Nucleotide Polymorphisms and Multivariate Traits in Attention Deficit Hyperactivity Disorder », The Multiple Facets of Partial Least Squares and Related Methods, Springer, 2016, p. 103-113.

LABBE, Aurélie, O. HUANG, Lam, INFANTE-RIVARD, Claire; « Transmission Ratio Distortion: A Neglected Phenomenon with Many Consequences in Genetic Analysis and Population Genetics », Epigenetics and Complex Traits, Springer New York, 2013, p. 265-285.

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